Louis’ recording debut was made for Columbia in 1949, and his music was released on a variety of independent labels through the 1950s, most notably recording for Sam Phillips’ Sun Records, for whom he recorded extensively as a backing musician for a wide variety of other singers as well as under his own name. His most notable recording was probably as guitarist on Rufus Thomas’s “Bear Cat”, recorded as an answer record to Big Mama Thornton’s “Hound Dog”, which reached No. 3 on the R&B chart and resulted in legal action for copyright infringement. He also shared writing credit for the song “Tiger Man”, which has been recorded by Elvis Presley, among others.
Around 1950 he took over the “Pepticon Boy” radio program on WDIA from B. B. King.
He was also known as “The Pepticon Boy” and “The Be-Bop Boy”.Louis died on August 5, 1957 in John Gaston Hospital, Memphis,at the age of 35, from tetanus contracted as a result of an infected cut to his thumb, sustained while working as an odd job man.